Product Name: Lenalidomide (CC-5013)
CAS No.:191732-72-6
Information: Antineoplastic agent, inhibits angiogenesis
Description: Lenalidomide (CC-5013) is an inhibitor of TNF-α secretion with IC50 of 13 nM.
Other Names: Revlimid,IMiD3,CC 5013,CDC-501,CDC 501
Chemical Name: 3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
Canonical SMILES: C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N
MF: C13H13N3O3
MW: 259.26
Purity: 99%
Grade Standard: Medicine Grade
Type: Antineoplastic Agents
Model Number: API- Lenalidomide
Solubility: Soluble in DMSO > 10 mM
Storage: Store at -20°C
General tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition: Evaluation sample solution : ship with blue ice. All other available size: ship with RT , or blue ice upon request
Background: Lenalidomide (also known as CC-5013), an oral derivative of thalidomide, is an antineoplastic agent exhibiting antitumor activity through a variety of mechanisms, including immune system activation, angiogenesis inhibition, and direct antineoplastic effects. It has been extensively studied for the treatment of multiple myeloma and myelodysplastic syndrome as well as lymphoproliferative disorders including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma. According to recent studies, Lnalidomide promotes and restores immune system function in CLL patients by inducing an overexpression of costimulatory molecules in leukemic lymphocytes to restore the humoral immunity and immunoglobulins production as well as improving the ability of T cells and leukemic cells to form synapses with T lymphocytes.
Brand Name: Huavet
Place of Origin: Shaanxi, China (Mainland)
USAGE: Pharmaceutical Intermediates
Inventory status: in stock
Shelf life: 2 years
Sample: Available
COA (Certificate of Analysis): Available
MSDS (Material Safety Data Sheet): Available
HPLC Spectrum: Available
ISO: Approved
GC: Available
NMR (Nuclear Magnetic Resonance): Available
Packaging Details:1g,5g,10g,50g,100g/bottle, 1kg/tin for trial order,25kg/drum for commercial quantity. Specific packing required by customer
Delivery Detail: Prompt shipment
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